COURSE SPECIFICATION
Faculty of Medicine- Mansoura University
(A) Administrative information
(1) Programme offering the course:
Master degree of cardiovascular
medicine
(2) Department offering the programme:
Cardiology Department
(3) Department responsible for teaching the
Pharmacology Department
course:
(4) Part of the programme:
1st Part
(5) Date of approval by the Department`s
council
(6) Date of last approval of programme
specification by Faculty council
(7) Course title:
Clinical Pharmacology
(8) Course code:
CARD 506
(9) Total teaching hours:
8 hours
(10) Credit hours
0.5 theoretical credit
1
(B) Professional information
(1) Course Aims:
The broad aims of the course are as follows: (either to be written in items or as a paragraph)
To provide the candidate with the pharmacological facts which are
appropriate to cardiovascular disorders for clinical reasoning, diagnosis and
management.
(2) Intended Learning Outcomes (ILOs):
Intended learning outcomes (ILOs); Are four main categories: knowledge & understanding to be
gained, intellectual qualities, professional/practical and transferable skills.
On successful completion of the course, the candidate will be able to:
A- Knowledge and Understanding
A2-To describe the Pharmacokinetics of drugs in cardiac patients .
A3- To explain cardiac drug interactions.
A4- To list the cardiac perceivable drugs during pregnancy and lactation
A5- To demonstrate the pharmacological details of the following Selected Drugs:
 Pharmacokinetics in cardiac patients
 Sympathetic and Parasympathetic Agonist and Antagonist
 Autacoids
 Cardiovascular drugs
 Drugs affecting blood
 Drugs affecting the Kidney
 Hormones
 Chemotherapy
 Drugs acting on central nervous system
B- Intellectual skills
B2- Apply the facts of pharmacology which are appropriate to clinical diagnosis and management
of cardiovascular diagnosis
C- Professional/practical skills
2
D- Communication & Transferable skills
D3- Work s effectively aa member or leader of professional group
(3) Course content:
Subjects
Lectures
1- General pharmacology :
 Pharmacokinetics in cardiac patients.
 Drugs in pregnancy and lactation.
2- Autonomic nervous system :
 Sympathomimetics and sympathetic antagonists.
 Parasympathomimetics and anticholinergics drugs.
3- Autacoids :
 Drugs affecting rennin — angiotensin — aldosterone system.
 Drugs affecting kallikrein — kinin system.
 Prostaglandins and other eicosanoids.
 Histamine antagonists.
 Serotonin antagonists
4- Cardiovascular drugs :
 Cardiac glycosides and other inotropic drugs
 Cardiac electrophysiology and antiarrhythmics.
 Antihvpertensive drugs: classification, mode of action, adverse effects.
 Management of hypertensive emergencies.
 Management of acute pulmonary oedema.
 Shock; syncope and hypotension.
 Antianginal drugs..
 Effect of drugs on electrocardiogram.
 Drugs in I.C.U.
5- Drugs affecting blood :
 Treatment of anemia.
 Coagulant, anticoagulants. thrombolytics and antiplatelet drugs.
 Antihyperlipidaemic agents.
6- Kidney :
 Diuretics:
 Drug-induced electrolyte imbalances.
 Nephrotoxic drugs
0.5
(hr)
3
0.5
1
2
0.5
0.5
Subjects
Lectures
7- Hormones :
 Insulin & Insulin resistance
 Management of diabetes mellitus and comas in diabetic patient:
 Diabetogenic agents
 Management of thyrotoxic heart disease.
 Corticosteroids in cardiovascular diseases.
 Relationship between hormonal contraceptives and C.V. disorders.
8- Chemotherapy :
 Sulfonamides and quinolones
 Monobactams antimicrobial and carbapenems.
 Aminoglycosides. Macrolides, Lincosamides, Tetracyclines.
 Chloramphenicol, Bactitracin, vancomycin and polymixins.
 Immunotherapy
9- Drugs acting on central nervous system :
 Opioid analgesics.
 Salicylates, Cholchin and others NSAID’s
 Benzodiazepines. Barbiturates and other sedative – hypnotics.
Total Teaching Hours
1
(hr)
(4) 0.Teaching methods:
4.1 : Lectures
(5) Assessment methods:
5.1:Written. (for assessment of knowledge and intelctual skills )
5.2: MCQ. (for assessment of knowledge and intelctual skills)
5.3: Oral. (for assessment of knowledge , intelctual skills and Transferable skills)
Assessment schedule:
1-Firist Exam : MCQ at end of Attendance Course
2-Final Exam at end of course:
2-a) Written exam
2-b) Oral exam
Percentage of each Assessment to the total mark:
1- MCQ Exam (20% of Written exam mark )
4
1
1
8
2-a) Written exam marks
2-b) Oral exam
(60 %: of total mark)
marks (40 % of total mark)
(6) References of the course:
6.1: Hand books: Member-Ship of Pharmacology Department Student Book
6.2: Text books: …………………………………………………………………
(7) Facilities and resources mandatory for course completion:
Lecture Rooms
Head of department: Prof. Dr.Karawan
Head of Cardiovascular department: Prof. Dr. Eman Elsafty
Date:
5