1. In this week’s experiment you will be performing an epoxidation on trans-stilbene with hydrogen
peroxide and 2,2,2-trifluoroacetophenone as a catalyst. What is the purpose of a catalyst in a reaction?
The purpose of a catalyst is to increase the speed that a reaction occurs. In this experiment, it is
2,2,2-trifluoroacetophenone. This is able to happen because the reaction is given a lower activation
energy which speeds up the reaction rate.
2. You will be using pH 11 buffer in the reaction. Is this an acidic or basic buffer?
How do we safely use it?
The pH 11 buffer is a base in this reaction. A base can cause heavy corrosive damage to skin and lead to
dangerous reactions when in contact with acids. To safely use this, wear the correct PPE at all times
(gloves, goggles, coat.) Always work in the fume hood to avoid inhaling fumes.
3. What is the purpose of hydrogen peroxide in the reaction?
The purpose of hydrogen peroxide in the reaction is to make dioxirane which is going to be our oxidizing.
4. How should we safely use and dispose of hydrogen peroxide?
Wear our PPE properly. Avoid mixing with combustible materials. Test it with test strips, quench it and
make sure it’s neutralized.
6. Drag the waste items to the appropriate waste container.
Solid Waste
Organic Waste
Aqueous Waste
Glass Waste
Trash Can
Used TLC plates
TLC eluent
Leftover chemicals
TLC capillaries
Drying Agent
Acetone
Aqueous layer after
extraction
Paper towels
Used weigh paper
Used pipette tips
Soiled gloves